MATTERHORN Trial Findings Signal Paradigm Shift in Early Gastric Cancer Care | Applied Clinical Trials Online

MATTERHORN Trial Findings

Research reveals perioperative immunotherapy with Imfinzi addresses unmet needs in gastric and GEJ cancers.

Nancy Ghattas, VP at AstraZeneca, discusses the Phase III MATTERHORN trial results, highlighting a 22% reduction in death risk.

Imfinzi-based perioperative regimen improved overall survival regardless of PD-L1 status.

This marks the first immunotherapy to show such benefit in this setting, paving the way for a new standard of care.

Author's summary: New trial findings shift gastric cancer care.

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Applied Clinical Trials Online Applied Clinical Trials Online — 2025-10-31

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