Ashleigh Gentle, a 10-time consecutive winner, will miss the Noosa Triathlon to focus on her T100 title push.
World champion Matthew Hauser will headline the event, which takes place on Sunday.
A decade-long event stranglehold has come to an end due to a scheduling squeeze.
Hauser will compete in the 1.5km swim, 40km cycle, and 10km victory lap at the 42nd Noosa staging.
Author's summary: Hauser to headline Noosa Triathlon after Gentle's withdrawal.