Galactus is destructive in The Fantastic Four: First Steps, but the Sacred Timeline is filled with characters who could beat him.
The Fantastic Four: First Steps arrived with a version of Galactus (Ralph Ineson) that is terrifyingly faithful to his comic book origins, a being of immense cosmic power whose very existence is a threat to all life.
The film portrays him as a force of nature, born before the universe itself and cursed with a relentless hunger that drives him into a never-ending quest for sustenance through the destruction of inhabited worlds.
This Devourer of Worlds is not merely a villain to be punched, and the movie brilliantly captures the scale of this threat.
Author's summary: Galactus is a powerful villain in The Fantastic Four.