Examining the CONVOKE Clinical Trial | AJMC

Examining the CONVOKE Clinical Trial

Panelists discuss the CONVOKE clinical trial, a 16-week study focusing on patients with negative symptoms of schizophrenia.

The trial incorporated patient input in app development, showing improvements in negative symptoms, depression, and cognitive function.

The CONVOKE clinical trial represents a significant advancement in developing targeted treatments for patients with negative symptoms of schizophrenia.

Trial Design

The 16-week trial enrolled patients with pure negative symptoms, excluding those with prominent positive symptoms, severe cognitive impairment, suicidality, or substance abuse.

Author's summary: The CONVOKE trial is a significant advancement in schizophrenia treatment.

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The American Journal of Managed Care The American Journal of Managed Care — 2025-10-14

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